Pioneering Anti-Aging Doctor and Turmeric Expert releases stunning announcement:
Whether you’re taking a turmeric supplement or
just considering it, you need to see my shocking findings.
A discovery that could mean the difference between
getting ALL or NONE of turmeric’s proven health benefits.
Hello, my name is Dr. Al Sears.
If you’ve read my newsletter Doctor’s House Call or any of my work, you know I’ve touted the healing benefits of turmeric — and specifically its active ingredient curcumin — for years.
Long before it became a fad, I’ve talked about how it’s more powerful than Big Pharma’s synthetic chemicals… without the side effects.
But get this:
Here at the Sears Institute for Anti-Aging Medicine, we do NOT use typical turmeric supplements.
You see, in spite of all of turmeric’s health benefits, scientists have established that it has one drawback:
It’s very difficult for our bodies to absorb.
Three specific things are needed to solve that:
The right kind of curcumin, specifically three of the most powerful curcuminoids, at the right dose: 1,000 mg per day
A proven delivery mechanism, shown by studies to get curcumin to your cells
And, perhaps most important all, similar ancient roots that MAGNIFY curcumin’s power. These are all things that most so-called “turmeric” supplements are lacking…
And the result is…
They do NOT metabolize in your body…
They do NOT get to your cells where it’s needed most…
And they do NOT cross your blood-brain barrier.
The sad truth: most turmeric users only get LESS THAN 5% of its true healing potential.
Isn’t it outrageous that even with the mountain of scientific research proving its benefits… we still lack access to a TRUE source of something so powerful — and so proven — as turmeric?
I thought so.
That’s why I tasked my research team with the challenge of forming the world’s best, most absorbable kind of turmeric…
Adding similar roots and herbs that synergistically work with turmeric.
And combining it with the right technology that delivers its maximum healing potential…
A special “delivery system” that transforms turmeric from a kitchen spice into the world’s most powerful healer.
After over 12 months of preparation, I believe we’ve formulated…
The Biggest Turmeric Breakthrough in 4,000 YEARS OF USE
I traveled the world to find three natural roots with outstanding health benefits.
And in just a moment, you’ll see why this is several generations ahead of conventional turmeric.
You’ll also discover…
How my patients are already seeing benefits you can’t get with most turmeric supplements.
3 other natural roots I added that are proven to AMPLIFY turmeric’s strength.
And how you too can begin to experience the TRUE potential of turmeric, for the first time ever.
I’ll reveal all of this, and more, in just a moment.
But before I do, allow me to share with you what turmeric can REALLY do…
In fact, it delivers no less than 619 ESSENTIAL BENEFITS for just about everything you can imagine.
Turmeric Delivers Over 619 Known Health Benefits
In a number of clinical trials, the results have been nothing short of remarkable, including…
Clinical Trials Prove Turmeric is More Powerful than The Popular Treatments in your Medicine Cabinet — Without Side Effects
Good cholesterol levels
Proof: In a study published in the journal Molecular Nutrition and Food Research, animals were given curcumin and a popular cholesterol solution over 18 weeks. The curcumin did better at supporting healthy cholesterol levels and gave no side effects. 15
Greater joint comfort
Proof: Published in the Journal of Alternative and Complementary Medicine, knee joint patients were given either a popular joint treatment or curcumin. Over the course of six weeks, both groups saw the exact same support of healthy joints, but there was one difference: the curcumin group saw zero side effects. 16
Normal erectile function
Proof: In a study published in the International Journal of Impotence Research, researchers treated animals in three groups: curcumin; a best-selling erectile solution; and a combination of the two. They found the curcumin group and the combination group “could enhance erectile function with more efficacy and more prolonged duration of
Sharp vision and healthy eyes
Proof: Researchers treated patients with vision problems using curcumin in one group and a popular eyesight therapy in the other. In three months, 100% of patients taking curcumin saw healthy middle layers of eyeball tissue. The other group only saw 86% success. What’s more, a follow-up done three years later found the curcumin group had greater long-term eye
More Upbeat Mood
Proof: In the journal Phytotherapy Research, researchers split up patients into three groups, giving one curcumin; one a popular mood booster; and the other a combination of the two. In the span of six weeks, curcumin and the popular mood booster worked equally well, but the combination of the two did better with fewer side effects. 19
Healthy Glucose Levels
Proof: Auburn University researchers compared curcumin to a popular blood sugar solution in their ability to balance glucose levels. They found curcumin was a stunning 10,000 times more powerful at supporting healthy glucose, and with no side effects.20
The list goes on and on.
This is just a small sample of what turmeric can do for you better — and safer — than anything else…
These are the sort of life-changing results my patients and I are now used to seeing all of the time.
But it’s only possible IF the turmeric is actually absorbable… and IF it crosses the blood-brain barrier.
Which is why I’ve added a new technology that’s proven to achieve both those things.
Something that a study at St. John’s University found enhances the power of turmeric by 2,000%.21
New Technology Enhances Turmeric’s Power by 2,000%
Researchers there compared blood levels of curcumin alone vs. combining it with bioperine…
And within 45 minutes of use, patients saw a stunning 2,000% increase in curcumin levels.
Not only that, it lasted longer in the bloodstream.
Now research is confirming that it actually WORKS better, too.
Special Technology Helps Curcumin Better Support Healthy Cholesterol and Triglyceride Levels
In one study, researchers took healthy animals, split them into three groups, and fed them a high-fat diet.22
In addition, group 2 received curcumin and group 3 received curcumin and piperine. And the results were breathtaking…
In over four weeks, the group that received curcumin and piperine saw NO changes to their blood levels.
In other words, the effects of a high-fat diet on their cholesterol and triglyceride levels were negligible.
In fact, their HDL (“good”) cholesterol levels actually increased!
That’s what curcumin is SUPPOSED to do. And piperine helps it get those results.
Enhances Mood, Happiness and Positive Attitude
In another study, researchers treated melancholic animals with curcumin or a combination with piperine.23
They found that the curcumin/piperine significantly boosted the subject’s dopamine and serotonin levels, which are essential to mood and happiness.
The study concludes,
“Curcumin along with piperine may prove to be a useful and potent natural approach in the management of mood.”
Superior at Maintaining Healthy Blood Sugar Levels
In another study, researchers treated animals in three groups: 1) curcumin alone 2) a standard blood sugar solution or 3) curcumin and piperine. 24
One month later, they analyzed the glucose levels and saw better results in the curcumin/piperine group compared to the other groups!
The curcumin/piperine group also saw…
Better support for healthy LDL cholesterol and triglycerides
Better support for healthy weight levels
And support for healthy glucose levels
And that’s just for starters…
A series of global studies are finding that curcumin and piperine together work better than curcumin alone to shield your mind and body from oxidative stress 25and neurotoxicity 26, and helps support healthy DNA. 27
All of which are shown to wreak havoc your health.
The research is clear:
This “bioperine” delivery system makes the difference between getting only a fraction of curcumin’s potential…
Or the full spectrum of its true healing benefit. And that means serious results like…
2’000% boost when curcumin and piperine are combined!
A longer, healthier life;
“Sharp-as-a-tack” thinking and memory recollection;
Easy, comfortable, pain-free mobility;
A happier, calmer mindset — free from stress, anxiety and worry;
Healthy blood sugar levels;
Healthy cholesterol and triglyceride levels;
Easy, smooth, hassle-free digestion;
Healthy kidneys, liver and lungs;
A slim, fit figure;
A healthy, ageless heart;
And much, much more.
You don’t enjoy results like these unless you have a proven delivery system for turmeric.
That’s why I refused to make a curcumin formula without including one, like so many supplement makers have.
But I took it a step further.
Two steps further, to be exact.
I’ve added two spices that belong to the curcumin “family”.
They’re both members of the elite group of rhizomes (root-like underground stems).
They’re both staples of ancient Ayurvedic medicine that go back over 4,000 years, just like curcumin.
And they both have similar proven benefits as curcumin, and act on age-related inflammation in a similar way.
So when all three are added together, they not only complement, but magnify curcumin’s results.
These are just a few reasons why I’ve made them key to my new formula: Curcumin Triple Burn.
Let me tell you a little bit about each right now… and why they make curcumin even more powerful…
Curcumin Amplifier #2:
Sacred Texts Call it “The Spice from Heaven”
The first is perhaps the world’s oldest medicinal spice, used going back 5,000 years at least.
It was first grown in Ancient China and India, where it was touted as a gift from God.
Then it spread all around the world as a luxury and powerful form of medicine.
In fact, ancient texts going back to the earliest Sanskrit literature praise it as an all-purpose healer.
So do medicinal books in ancient Rome, Greece and the Middle East.
The Quran calls it a “spice from heaven.”
Most of the prescriptions written in Chinese traditional medicine included a combination of herbs.
And this one was in over half of them!
The symbol for ginger is found in
Traditional Chinese Medicine.
Explorer Marco Polo thoroughly documented its cultivation and use in his expedition to East Asia.
The Roman Empire considered it a luxury reserved for the rich.
And it was very expensive: one pound of this spice was equivalent to a whole sheep or cow.
I’m talking about ginger, of course.
But not the kind in your spice cabinet, cookies or soda. Nor just any plain ol’ ginger supplement.
Instead, I recommend a concentrated dose of its most powerful medicinal compound: gingerol.
Just like curcumin is the molecular “hero” in turmeric, so too is gingerol the powerhouse inside ginger.
And now scientists are finding that the ancients were more right than you could imagine. Some of its benefits include…
Nausea relief 28
Fast metabolism and healthy weight levels 29
Ginger: Nature’s Multi-Tool.
Healthy blood flow and circulation
Smooth, comfortable joints 30
Healthy blood pressure levels 31
Healthy cholesterol and triglyceride levels 32
Smooth, hassle-free digestion
Healthy blood sugar levels 33
Improved insulin support 34
That’s why I call ginger “nature’s multi-tool.” There’s not much it can’t do or help. And now we know why…
You see, ginger “switches off” the genes that cause age-related inflammation — much like curcumin.
The most powerful of these is the molecule Nuclear Factor-kappa beta (NF-kB) — the body’s inflammation command center.
Shuts Down Our Body’s “Inflammation Command Center”
NF-kB is the “switch” that activates over 400 of our body’s pro-inflammatory genes. Including the enzymes COX-2, iNOS and LOX.
As a result it provides our body the blueprint for regulating its inflammatory response.
Big Pharma considers it the “Holy Grail” for age-related inflammation. But they’ve failed to reliably and safely target it using drugs. 35
Because nature already designed at least two powerful NF-kB deactivators: curcumin and ginger.
Curcumin’s effects on NF-kB are renowned. But it’s hardly known that ginger does the exact same thing. 36
In combination they’re a powerful duo against the leading cause of age-related inflammation.
That’s also why studies point to ginger as such a powerful joint remedy.
One double-blind study treated 120 joint patients with either a placebo or gingerol.
In just 12 weeks, the ginger group saw remarkably healthy inflammation markers.
The researchers conclude it’s because the gingerol extract deactivated the NF-kB gene. 37
The result: its joint-relief benefits are second to none.
In fact, researchers at the University of Miami are now saying that ginger could be a first-line joint treatment. 38
In a double-blind study, they compared gingerol extract to a placebo in 261 knee joint patients.
They found the ginger supported healthy joint comfort by 40% over the placebo… in just six weeks.
“Research shows that ginger affects certain inflammatory processes at a cellular level,” says the study’s lead author, Roy Altman, MD. 39
What makes ginger so powerful?
Most joint solutions simply block the formation of certain inflammatory compounds.
Ginger, on the other hand, not only “turns off” the master commander of age-related inflammation…
But also has antioxidant effects that break down existing inflammation and acidity in the fluid within the joints.
That’s why the researchers concluded its work superior to popular joint treatments.
“Ginger has anti-inflammatory… and antioxidant activities, as well as a small amount of [pain relieving] property,” says Roberta Lee, MD, vice chair of the Department of Integrative Medicine at Mount Sinai Beth Israel.
But ginger didn’t deliver these results alone.
In fact, there was another spice used in the study that went overlooked.
Curcumin’s other, lesser-known relative.
It’s the third member of the elite group of rhizome plants.
In combination with ginger, the research shows it works wonders on a variety of health concerns.
Like curcumin and ginger, it has a 4,000-year history of use in ancient medicine systems.
So it was a no-brainer as my third curcumin amplifier.
Curcumin Amplifier #3:
“The Spice of Life”
Galangal: “The gold mine of future therapeutics.”
It’s called galangal.
Just like ginger, galangal warms the body and aids in digestion. It’s also a powerful anti-nausea remedy.
Of course, it also shows similar antioxidant, anti-inflammatory and antimicrobial powers. 40
Since it doesn’t have the same recognition as either curcumin or ginger, it hasn’t been studied so extensively.
But researchers are already calling it
“the gold mine of future therapeutics.” 41
It was not until the 800s AD that galangal found its way into European hands through spice trade with the East.
The famed St. Hildegard, a renowned healer and expert in herbal medicine, recognized galangal’s powers and dubbed it the “Spice of Life.”
A cure-all for many conditions that ravaged Europe at the time.
In fact, amidst the Bubonic Plague that destroyed a third of Europe’s population, people created potential life-saving medicines.
Medicines that included galangal due to its antimicrobial properties.
One of the most famous legends was that of the “Four Thieves” — four men who went around sacking the homes of plague victims, but never contracted the plague.
Their immunity was credited to the “Four Thieves Oil” they designed, which included galangal.
That’s just a few reasons why I’ve made galangal one of the key ingredients of my new breakthrough.
Again, I call it Curcumin Triple Burn.
The “Next Generation” of Curcumin is Here
In all my years on the cutting edge of natural health, I’ve never seen a curcumin formula like it.
None that include a therapeutic dose of curcuminoids… delivery technology proven to enhance its absorption by 2,000%… or spices that complement and amplify curcumin’s healing potential.
But that’s not all.
I’ve added one more extra “kicker” to boost this formula’s results.
Bonus Curcumin Amplifier!
This final ingredient belongs to an elite class of herbs called “adaptogens.”
And just as the name sounds, it adapts to what your body needs, at any given moment.
Need sleep? Energy? Stamina? Stress relief?
These herbs are so smart, and so powerful, they deliver it you. And the effects last all day long.
Adaptogens recently started gaining ground in America, but in India, Russia and China they’ve been a staple form of medicine for thousands of years.
Holy Basil: The Wonder Herb.
Over 25 herbs are classified as adaptogens. One in particular is being recognized as a leader in Ayurvedic medicine.
And I’ve made this “smart herb” the platoon leader of my curcumin formula.
So while the curcumin, the two other spices, and the delivery system are the elite soldiers…
This herb harnesses their full healing potential… commands exactly where they target… and keeps them disciplined, working all throughout the day, in any situation, for whatever your body needs.
Its scientific name is Ocimum Sanctum. It’s better known as Holy Basil, or “Tulsi.”
Within Ayurveda, Holy Basil is known as “The Incomparable One,” “Mother Medicine of Nature,” and “The Queen of Herbs.”
And it’s revered as an “elixir of life” without equal in its healing powers, which are now being confirmed by modern science.
One group of scientists that reviewed all of the studies conducted on Holy Basil even called it…
“The Wonder Herb” 42
Another group of researchers call it an “herb for all reasons.” 43 And it’s not hard to see why.
The World’s Ultimate Stress-Buster
Tulsi – just like other adaptogens – is proven to balance serum levels of cortisol.44 And that’s no small matter.
The so-called “stress hormone” is proven to wreak havoc on your mind and body.
Psychology Today is even calling cortisol “Public Enemy No. 1.” 45
And now we know why it’s so dangerous…
You see, it was previously thought cortisol overload simply broke down our immune system… causing colds.
But it’s not so simple.
According to groundbreaking new research at Carnegie Mellon University, high levels of cortisol – caused by chronic stress – decrease the sensitivity of our immune cells to hormone signaling.
This triggers the immune system’s cytokine cells to release a non-stop inflammatory response.
The illness that results is simply the “side effect” of the runaway inflammation. 46
Perhaps that’s why stress has been implicated in just about every health concern imaginable.
And why Holy Basil – a proven cortisol regulator – is proven to work on so many age-related conditions.
Take one study done on blood sugar patients. 47
Half of the patients were given 2.5 g of holy basil leaf powder daily, and the other half were given a placebo for four weeks.
Compared to the control group, the group administered holy basil experienced some amazing results.
Not only did fasting glucose and post-meal glucose reach normal healthy levels. They saw enhanced support for healthy cholesterol levels during the treatment as well!
In another study, holy basil extract (500 mg twice daily) enhanced mood in unhappy middle-aged adults.
It also improved the “willingness to adjust” to circumstances beyond their control – a key factor in stress-induced sadness. 48
And it’s a powerful brain booster, too – much like curcumin.
In a human study, researchers found that 300 mg a day of holy basil leaf extract produced a significant improvement in many different cognitive parameters, including reaction time and error rates on standardized tests, as well as on a test that measures anxiety. 49
This is the final ingredient in my new curcumin breakthrough formula: Curcumin Triple Burn.
Amazing: What You Get in Every Single Pill
With every single dose of Curcumin Triple Burn you get…
At last! The full power of turmeric unleashed… And for just $1
Nothing quite has health-concerned individuals so excited as turmeric. And for good reason…
It seems like every day the new science shows its healing potential is second to none.
There’s almost nothing it can’t do for your body… no result it can’t deliver… and no health concern it doesn’t address.
That’s why I’ve gone above and beyond to not only release turmeric’s MAXIMUM potential…
But to make it even more affordable, and accessible to YOU.
As you may know, I’ve referred to curcumin as the $1 pill. And that’s certainly true, at least for most formulas.
Yet even with everything I’ve added to this formula…
Even with the complementary herbs…
Even with the 2,000% boosting technology… and the adaptogen to harness its full potential…
On top of a therapeutic 1,000 mg dose of the three most powerful curcuminoids…
I’m going to stand by my $1 reference with an incredible introductory offer, as you’ll see in a moment.
But first, I have to admit. There’s one catch.
Urgent: ONLY 243 WILL GET A SHOT TO TRY
Curcumin Triple Burn
The $1 pill is here!
At this moment, I only have a shipment of 243 bottles on hand.
Which means only a handful of people are going to get these first orders at this low price.
Once this shipment runs out, I can’t guarantee that I can still offer it for $1 per pill.
After all, this is not your ordinary curcumin.
And even at $2, with all of the health concerns it solves, many would consider it a bargain.
Not only that, I’ve sent this message to over 200,000 people today, which means less than 1% will get a shot to claim their spot.
So YOU must take action quickly if you want to experience turmeric’s life-changing benefits…
In order to guarantee shipments for my VIP Auto Delivery members, we may have to shut down this presentation in the next few days… possibly even tonight.
That’s why—if you do get the opportunity to claim your supply—I urge you to take advantage of our discount on multi-bottle orders.
I mean, it’s 100% guaranteed or your money back, so why mess around?
When you order right now, you’ll get a free membership in my VIP Auto Delivery Service, which means you don’t have to worry about re-ordering. Just when your initial order is about to run out, our system will alert us and we’ll securely re-charge your card to rush you a fresh supply of Curcumin Triple Burn.
You can cancel your delivery or change the schedule at any time, for any reason. Auto Delivery is simply the only way we can guarantee you the best price and a steady supply. And I think you’ll really love it—because it saves you the hassles of reordering—and it entitles you to FREE shipping for as long as you remain a member.
Yep—as an Auto Delivery VIP, you won’t pay a cent for shipping… ever.
So once you try Curcumin Triple Burn and love it—you don’t have to lift a finger to keep getting it.
Of course, it’s your call. And you have plenty of time to try it.
At any time in the next 90 days, for any reason—just send your current bottle back, and we’ll send you a refund of every penny of the purchase price.
So there’s really nothing to think over—you don’t even have to decide anything right now. Just try it!
And if you don’t agree that Curcumin Triple Burn delivers the full promise of turmeric’s benefits… if you’re not feeling healthier, happier and more energized than you have in decades…
Just say the word and get your money back.
It’s simple: if it doesn’t work for you, you don’t pay for it.
Introducing… The $1 Pill for Everything
Well, today — if you select the three-month, Auto Delivery option — you can lock in this curcumin breakthrough for just $1 a day. That’s just 50 cents per pill!
And I recommend you do so, because once you begin experience the real potential of curcumin… looking and feeling many years younger and healthier….
You’ll only have one concern left….
How can I get more?
And because I can’t promise I’ll have another shipment between now and three months…
Because the VIP Auto Delivery members get first dibs on the next supply…
And because you lock in the $1 price — a deal you will NOT find anywhere else…
The option is a no-brainer.
So please, don’t delay. I really want you to take advantage of my offer right now.
I want you to start enjoying every turmeric has to offer…
I want you to experience its unparalleled 619 proven health benefits…
I want you to start feeling younger brain power, energy and vitality.
So don’t wait any longer. Click the Order Button below NOW.
To Your Good Health,
Al Sears, MD, CNS
BEST DEAL: Become a Curcumin Triple Burn VIP! Huge VIP Savings, Plus FREE Shipping for LIFE
I’ll save 30% by joining the Curcumin Triple Burn 3-month Auto Delivery Program,which includes a locked-in discount and FREE Shipping for Life.
I’ll get 3 bottles of Curcumin Triple Burn shipped right to my door every 3 months for just $29.95 each for a total of $89.85. And I will get this discounted price along with FREE shipping for as long as I take Curcumin Triple Burn.
For my convenience, my credit card will be automatically charged with each shipment.
I’ll never have to worry about reordering and I can cancel at any time!
That’s an annual savings of over $263!
I’ll get 3 bottles of Curcumin Triple Burn shipped right to my door for only $38.65 each, PLUS shipping and handling.
I’ll get 1 bottle of Curcumin Triple Burn for $42.95 PLUS shipping and handling.
Meet Al Sears, M.D.
Uniquely Qualified to Keep You Healthier for Life
Al Sears, MD is America’s #1 anti-aging doctor. He’s made it his life’s work to challenge conventional medical beliefs and bring his patients the latest breakthroughs in natural cures and remedies to diseases once thought to be “incurable.”
Dr. Sears takes a fresh, novel approach to patient health and wellness. Our environment has changed for the worse — and it’s affecting your health. He helps patients escape accelerated aging caused by modern toxins, chemicals and other hormonal threats you unknowingly face every day.
Every year, he travels over 20,000 miles to the most remote regions of the world searching for natural healing secrets unknown or ignored by mainstream medicine.
Since 1999, Dr. Sears has published 35 books and reports on health and wellness. He has millions of loyal readers spread over 163 countries.
Today he writes and publishes two monthly e-Newsletters, Confidential Cures and Anti-Aging Confidential for Women, and a daily email broadcast, Doctor’s House Call, with more than 500,000 subscribers. He has also appeared on more than 50 national radio programs, ABC News, CNN and ESPN.
Dr. Sears was one of the first to be board-certified by the American Academy of Anti-Aging Medicine (A4M). More than 25,000 patients travel from all around the world to visit him at the Sears Institute for Anti-Aging Medicine in beautiful Royal Palm Beach, Florida.
Recently, Dr. Sears proved you can affect the way you age by controlling the length of your telomeres. He made history as the first MD to introduce the Nobel prize-winning, anti-aging breakthrough of our time, telomere DNA therapy, to the general public. And now he’s working with the leading scientists in the field of telomere biology to further define how this incredible technology will shape the future of anti-aging medicine.
HERE’S WHAT INDUSTRY EXPERTS ARE SAYING ABOUT DR. SEARS
“Dr. Sears blows away the conventional medical wisdom…”
— Ronald Klatz, MD, DO, Founder and President, American Academy of Anti-Aging Medicine
“Dr. Sears has distinguished himself as a leader in the area of Anti-Aging Medicine and recently in cell and telomere biology…”
— Frederic J. Vagnini, MD, FACS, Medical Director of the Heart, Diabetes and Weight Loss Centers of NY
“Dr. Sears masterfully explains how we can flip the switches that allow access to the store of human vitality that resides within each one of us. We understood how to do this when we were young and now Dr. Sears gives us the evidence-based means to tap into our potency, strength, and stamina with intention.”
— Paul L. Hester, MD, MBA
“Dr. Al Sears really gets it. What a refreshing breath of fresh air…”
— Jonny Bowden, author, Living the Low Carb Life: From Atkins to the Zone Choosing the Diet That’s Right for You
1 Cox KH, Pipingas A, Scholey AB. “Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population.” J Psychopharmacol. 2014
2 Chuengsamarn S, et al. Curcumin extract for prevention of type 2 diabetes. Diabetes Care. 2012 Nov ;35(11):2121-7.
3 Akazawa N, et al. Curcumin ingestion and exercise training improve vascular endothelial function in postmenopausal women. Nutr Res. 2012 Oct ;32(10):795-9.
4 Yang YS. Lipid-lowering effects of curcumin in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled trial. Phytother Res 2014 Dec;28(12):1770-7.
5 Chandrashekara KT, et al, “Curcumin enhances parental reproductive lifespan and progeny viability in Drosophila melanogaster,” Age, vol. 36, no. 5, 2014
6 Belcaro G, et al. Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Alternative Medicine Review 2010 Dec;15(4):337-44.
7 Thring et al. Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants. BMC Complement Altern Med 2009, 9:27 doi:10.1186/1472-6882-9-27.
8 YBundy R, Walker AF, Middleton RW, Booth J. “Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults: a pilot study.” Journal of Alternative & Complementary Medicine. 10(6):1015-8, 2004
9 McFarlin BK, Venable AS, Henning AL, Best Sampson JN, Pennel K, Vingren JL, Hill DW. Reduced inflammatory and muscle damage biomarkers following oral supplementation with bioavailable curcumin. BBA Clinical 2016; 5:72-78.
10 Lal B, Kapoor AK, Asthana OP. Efficacy of curcumin in the management of chronic anterior uveitis. Phytother Res. 1999 Jun;13(4):318-22.
11 Xiao Z, Zhang A, Lin J, Zheng Z, Shi X, Di W, et al. (2014) Telomerase: A Target for Therapeutic Effects of Curcumin and a Curcumin Derivative in Aβ1-42 Insult In Vitro. PLoS ONE 9(7).
12 “Curcumin May Prevent Clogged Arteries.” WebMd.com, 20 July 2009.
13 Khajehdehi P. Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study. J Ren Nutr. 2012 Jan;22(1):50-7.
14 Wanwarang W, et al. Effects of curcuminoids on frequency of acute myocardial infarction after coronary artery bypass grafting. Am J Cardiol. 2012 Jul 1 ;110(1):40-4.
15 Shin SK, HA TY, McGregor RA, Choi MS. Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism. Mol Nutr Food Res. 2011 Nov 7.
16 Kuptniratsaikul V, et al. Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis. J Altern Complement Med. 2009;15(8):891-897
17 Zaahkouk AMS, et al, “Efficacy of a novel water-soluble curcumin derivative versus sildenafil citrate in mediating erectile function,” International Journal Of Impotence Research, vol. 27, no. 1, pp. 9–15, 2015.
18 Lal B et al. Efficacy of curcumin in the management of chronic anterior uveitis. Phytother Res 1999 Jun;13(4):318-22.
19 Sanmukhani J, et al. Efficacy and Safety of Curcumin in Major Depressive Disorder: A Randomized Controlled Trial. Phytother Res. 2013 Jul 6.
20 Kim, T., Davis, J., Zhang, A.J., He, X., and Mathews, S.T. (2009) Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells. Biophys. Res. Commun. 388, 377–382.
21 Shoba G, et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998 May;64(4):353-6.
22 Tu, Y, et al. Piperine potentiates the hypocholesterolemic effect of curcumin in rats fed on a high fat diet. Exp Ther Med. 2014 Jul;8(1):260-266.
23 Bhutani MK, et al. Anti-depressant like effect of curcumin and its combination with piperine in unpredictable chronic stress-induced behavioral, biochemical and neurochemical changes. Pharmacol Biochem Behav. 2009 Mar;92(1):39-43.
24 Kaur G, et al. Influence of Piperine and Quercetin on Antidiabetic Potential of Curcumin. J Complement Integr Med. 2016 Jun 25.
25 Panahi Y, et al. Effects of Curcuminoids-Piperine Combination on Systemic Oxidative Stress, Clinical Symptoms and Quality of Life in Subjects with Chronic Pulmonary Complications Due to Sulfur Mustard: A Randomized Controlled Trial. J Diet Suppl. 2016;13(1):93-105.
26 Singh S, et al. Piperine Enhances the Protective Effect of Curcumin Against 3-NP Induced Neurotoxicity: Possible Neurotransmitters Modulation Mechanism. Neurochem Res. 2015 Aug;40(8):1758-66.
27 Sehgal A, et al. Combined effects of curcumin and piperine in ameliorating benzo(a)pyrene induced DNA damage. Food Chem Toxicol. 2011 Nov;49(11):3002-6.
28 Ryan JL, et al. Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients. Support Care Cancer. 2012 Jul;20(7):1479-89.
29 Mansour MS, et al. Ginger consumption enhances the thermic effect of food and promotes feelings of satiety without affecting metabolic and hormonal parameters in overweight men: a pilot study. Metabolism. 2012 Oct;61(10):1347-52.
30 Altman RD, et al. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum. 2001 Nov;44(11):2531-8.
31 Akinyemi AJ, et al. Dietary Supplementation of Ginger and Turmeric Rhizomes Modulates Platelets Ectonucleotidase and Adenosine Deaminase Activities in Normotensive and Hypertensive Rats. Phytother Res. 2016 Jul;30(7):1156-63.
32 Tahereh A, et al. The effect of ginger consumption on glycemic status, lipid profile and some inflammatory markers in patients with type 2 diabetes mellitus. Int J Food Sci Nutr. 2014.
35 Lawrence T. The nuclear factor NF-kappaB pathway in inflammation. Cold Spring Harb Perspect Biol. 2009 Dec;1(6).
36 Lee HY, et al. 1-Dehydro--gingerdione from ginger inhibits IKKβ activity for NF-κB activation and suppresses NF-κB-regulated expression of inflammatory genes. Br J Pharmacol. 2012 Sep;167(1):128-40.
37 Naderi Z, et al. Effect of ginger powder supplementation on nitric oxide and C-reactive protein in elderly knee osteoarthritis patients: A 12-week double-blind randomized placebo-controlled clinical trial. J Tradit Complement Med. 2015 Jan 28;6(3):199-203.
38 Altman RD, et al. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum. 2001 Nov;44(11):2531–8.
39 “Health Benefits of Ginger.” Arthritis Today Magazine, 22 Jan. 2016.
40 Altman RD, et al. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum. 2001 Nov;44(11):2531–8.
41 Ghosh, S. Alpinia: the gold mine of future therapeutics. 3 Biotech. 2013 Jun; 3(3): 173–185.
42 Sai Krishna. G., et al. “Tulsi” – the Wonder Herb (Pharmacological Activities of Ocimum Sanctum). American Journal of Ethnomedicine, 2014, Vol. 1, No. 1, 089-095
43 Cohen MM, et al. Tulsi – Ocimum sanctum: A herb for all reasons. J Ayurveda Integr Med. 2014 Oct-Dec; 5(4): 251–259.
44 Jothie Richard E, Illuri R, Bethapudi B, et al. Anti-stress activity of Ocimum sanctum: Possible effects on hypothalamic-pituitary-adrenal axis. Phytother Res. 2016;30(5):805-14.
45 “Cortisol: Why the Stress Hormone is Public Enemy No. 1.” Psychology Today, 22 Jan. 2013.
46 Cohen, S, et al. Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk. PNAS, April 2, 2012
47 Agrawal P, et al. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther. 1996 Sep;34(9):406-9.
48 Bhattacharyya D, Sur TK, Jana U, et al. Controlled programmed trial of Ocimum sanctum leaf on generalized anxiety disorders. Nepal Med Coll J. 2008;10(3):176-9.
49 Sampath S, Mahapatra SC, Padhi MM, et al. Holy basil (Ocimum sanctum Linn.) leaf extract enhances specific cognitive parameters in healthy adult volunteers: A placebo controlled study. Indian J Physiol Pharmacol. 2015;59(1):69-77.
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Al Sears, M.D., is a practicing physician with extensive experience in the fields of complementary and natural healthcare. The recommendation and materials on this site represent his opinion based on his years of practicing medicine. Any recommendations are not intended to replace the advice of your physician. You are encouraged to seek advice from a competent medical professional regarding the applicability of any recommendations with regard to your symptoms or condition. It is important that you do not reduce, change or discontinue any medication or treatment without consulting your physician first.